An open-label phase I trial to study side effects and the best dose of AT-101 to give with temozolomide with or without radiation therapy
This study is being conducted at multiple sites within the United States.
This trial is being sponsored by Ascenta Therapeutics, Inc., and the National Cancer Institute.
AT-101 activates a pathway inside cancer cells resulting in the death of those cells. It is given by mouth in the form of pills.
Temozolomide is a chemotherapy agent.
Contact your physician. Your physician will be able to advise you about participating.
NCT00390403